coreopsis tinctoria tea
eCollection 2015. Background: Coreopsis tinctoria Nutt is an ethnomedicine widely used in Xinjiang, China. Our previous study confirmed that the ethyl acetate extract of Coreopsis tinctoria (AC) had a protective effect on diabetic nephropathy (DN) in an in vivo experiment.
Prevalence and risk factors of diabetic nephropathy in omani type-2 diabetics in Al-dakhiliyah region.
The Flower Tea Coreopsis tinctoria Increases Insulin Sensitivity and Regulates Hepatic Metabolism in Rats Fed a High-Fat Diet Use the link below to share a full-text version of this article with your friends and colleagues.
2015 Sep 7;15:314. doi: 10.1186/s12906-015-0826-x. Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment.
2019 Dec 30;21(1):263. doi: 10.3390/ijms21010263. 2015 Mar 24;10(3):e0122661. Unlimited viewing of the article/chapter PDF and any associated supplements and figures. USA.gov.
Coreopsis tinctoria Nutt (C. tinctoria), a member of the Chrysanthemum family, usually grows in the Karakoram Mountain in the south of Xinjiang, China (Guo et al., 2015). There is a long history for C. tinctoria buds used as a folk medicine in the treatment of diabetes, hypertension and hyperlipidemia (Ma et al., 2016, Tian et al., 2019). Diabetes Care. Ethnopharmacological relevance. Korean J Physiol Pharmacol. Biomed Pharmacother. View the article PDF and any associated supplements and figures for a period of 48 hours. HBZY-1 cells were pretreated with AC and marein for 2 h, and then stimulated with PDTC, an NF-κB inhibitor followed by NG or HG exposure for 24 h. Equal amounts of lysate were subjected to western blotting analysis to determine NF-κB P-65 and MCP-1. Marein may be one of the bioactive compounds in AC. 2017;27:1451–1454.
Our previous study confirmed that the ethyl acetate extract of Coreopsis tinctoria (AC) had a protective effect on diabetic nephropathy (DN) in an in vivo experiment. In recent years, Coreopsis tinctoria has become a popular herbal tea material in the functional food market because of its remarkable pharmacological activities. A HG-induced barrier dysfunction model in rat mesangial cells (HBZY-1) was established. 2018 May;101:670-681. doi: 10.1016/j.biopha.2018.02.090. Rapa SF, Di Iorio BR, Campiglia P, Heidland A, Marzocco S. Int J Mol Sci.
Diabetic kidney disease: a report from an ADA consensus conference. Effect of AC and marein on p-Smad2, p-Smad3 and Smad4 expressions in HG-treated HBZY-1 cells by western blots. Therefore, 7 compounds were identified as major antioxidant biomarkers for quality control of C. tinctoria. Chian CW, Lee YS, Lee YJ, Chen YH, Wang CP, Lee WC, Lee HJ. 2014;37:2864–2883. Note: Values were expressed as the mean ± SD. Working off-campus?
Here we aim to elucidate the protective mechanism of AC and marein, the main ingredient in Coreopsis tinctoria on renal fibrosis and inflammation in vitro under high glucose (HG) conditions.
NIH Inflammation and Oxidative Stress in Chronic Kidney Disease-Potential Therapeutic Role of Minerals, Vitamins and Plant-Derived Metabolites. Iwai T, Miyazaki M, Yamada G, Nakayama M, Yamamoto T, Satoh M, et al. 2012;27:212–216. The cells were exposed to AC and marein and/or HG for 24 h. Then, the renal protective effects of AC and marein via transforming growth factor-β1 (TGF-β1)/Smads, AMP-activated kinase protein (AMPK), and nuclear factor kappa beta (NF-κB) signaling were assessed. MicroRNA-140-5p ameliorates the high glucose-induced apoptosis and inflammation through suppressing TLR4/NF-κB signaling pathway in human renal tubular epithelial cells. The invention relates to medlar coreopsis tinctoria flower tea, which is a tea bag formed by uniformly mixing the following raw materials in percentage by weight: 65-73% of purified and impurity-removed coreopsis tinctoria flowers, 8-12% of xylitol, and 18-24% of medlar extract. “Gongju” and “Hangju” in this study. Results showed that 7 compounds made up the major contributions of antioxidant activity in C. tinctoria, including okanin, isookanin, marein, flavanomarein, 5,7,3′,5′‐tetrahydroxyflavanone‐7‐O‐glucoside, 3,5‐dicaffeoylquinic acid, and chlorogenic acid.
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